relationship between the human t- lymphotropic virus and myeloid leukemia, mycobacterium tuberculosis

Authors

saman ayoubi

mycobacteriology research centre, national research institute of tuberculosis and lung disease (nritld), shahid beheshti university of medical sciences, tehran, iran mohammad sadegh hashemzadeh

applied virology research center, baqiyatallah university of medical sciences, tehran, iran omid lakzaie azar

fajr milk, industry co., golestan sabah, sabah, gonbad, iran fatemeh naeimpour

department of mycology, fac of vet. med, science and research branch of islamic azad university, tehran, iran nasim padasht

abstract

human t-cell lymphotropic virus type 1 , 2 (htlv-1, 2) is endemic in particular areas of the world in which it is associated with myeloid leukemia.in this study, we described the prevalence of htlv-1, 2 in myeloid leukemia and mycobacterium tuberculosis in iran. we have worked with tissue and blood samples for 2 years. these were the same samples which were positive for myeloid leukemia, mycobacterium tuberculosis,htlv and were collected from imam khomeini hospital in tehran, iran. 100 cases were investigated (58% males, 42% females), the age of these samples were within 5 to 89 years old.in 65.7 percent of the leukemia rate htlv-1 has been positive. five cases (54%) were myeloid leukemia, 36.4% cases were not myeloid leukemia and 3 out of 8 cases (27.9%) unclassified lymphomas, were positive respectively. all 6 cases (100%) were adults with acute t-cell leukemia/lymphoma (atll) and mycobacterium tuberculosis were positive. among all cases, just one case has been positive for chronic myeloid leukemia and myeloproliferative disruption. positive htlv-1- show more in older ages than younger one. at younger ages offers less than negative items. according to our results, in iran htlv-1, 2 is dramatically related to myeloid leukemia, and more studies are required for accurate connection with myeloma diseases and this area.

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Journal title:
international journal of advanced biological and biomedical research

جلد ۴، شماره ۲، صفحات ۱۴۳-۱۴۸

Keywords
[ ' h t l v ' , 1 , 2 , ' m y e l o i d l e u k e m i a ' , ' m y e l o m a ' ]

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