relationship between the human t- lymphotropic virus and myeloid leukemia, mycobacterium tuberculosis
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abstract
human t-cell lymphotropic virus type 1 , 2 (htlv-1, 2) is endemic in particular areas of the world in which it is associated with myeloid leukemia.in this study, we described the prevalence of htlv-1, 2 in myeloid leukemia and mycobacterium tuberculosis in iran. we have worked with tissue and blood samples for 2 years. these were the same samples which were positive for myeloid leukemia, mycobacterium tuberculosis,htlv and were collected from imam khomeini hospital in tehran, iran. 100 cases were investigated (58% males, 42% females), the age of these samples were within 5 to 89 years old.in 65.7 percent of the leukemia rate htlv-1 has been positive. five cases (54%) were myeloid leukemia, 36.4% cases were not myeloid leukemia and 3 out of 8 cases (27.9%) unclassified lymphomas, were positive respectively. all 6 cases (100%) were adults with acute t-cell leukemia/lymphoma (atll) and mycobacterium tuberculosis were positive. among all cases, just one case has been positive for chronic myeloid leukemia and myeloproliferative disruption. positive htlv-1- show more in older ages than younger one. at younger ages offers less than negative items. according to our results, in iran htlv-1, 2 is dramatically related to myeloid leukemia, and more studies are required for accurate connection with myeloma diseases and this area.
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Journal title:
international journal of advanced biological and biomedical researchجلد ۴، شماره ۲، صفحات ۱۴۳-۱۴۸
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